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KPV's primary mechanism involves inhibiting NF-kB activation

However, the sample available at the 6-year follow-up was not entirely comparable to the one selected for the main analyses, as it included subjects with a substantially better health profile (indicative of survival bias) compared to those lost to follow-up

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Additionally, the psychological aspects of BEDincluding emotional regulation difficulties and the functional role of binge eatingmay not be adequately addressed by medication alone